Glossary entry

French term or phrase:

immunoglobulines physiologiques

English translation:

uninvolved immunoglobulins

Added to glossary by joanna menda
Dec 12, 2017 23:43
6 yrs ago
2 viewers *
French term

immunoglobulines physiologiques

French to English Medical Medical (general) Serum protein electrophoresis
Hi,

The patient suffers from multiple myeloma.
The test results shows a moderately significant gamma2 kappa2 monoclonal gammopathy with an "effondrement des immunoglobulines physiologiques"

I am really confused with the use of "physiologique" in this context....

Would "drastic drop in immunoglobulin levels" be ok?

Thanks

Joanna

Discussion

liz askew Dec 13, 2017:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2326812/
by M SHIMODA - ‎1999 - ‎Cited by 32 - ‎Related articles
To understand the biological function of natural immunoglobulin A (IgA) antibodies in Peyer's patches (PP), we generated IgA monoclonal antibody (mAb) clones from the PP of normal, unimmunized, specific pathogen-free BALB/c mice and examined their reactivities by enzyme-linked immunosorbent assay (ELISA).
liz askew Dec 13, 2017:
FWIW, I think they are talking about "natural immunoglobulin antibodies".

Proposed translations

+2
11 hrs
Selected

uninvolved immunoglobulins

. The term "uninvolved" is widely used in this context to indicate the patient's normal immunoglobulins, whose level is often sharply reduced in MM.
See https://www.nature.com/articles/bcj201746
Peer comment(s):

agree Anne Schulz
2 hrs
Thank you Anne
agree Sue Davis
8 hrs
Thank you Sue
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4 KudoZ points awarded for this answer. Comment: "Thanks dwt2"
6 mins

drastic drop in immunoglobulin levels (compared to normal physiological levels)

immunoglobulines g, a, m - Biomnis
https://www.biomnis.com/referentiel/liendoc/precis/IMMUNOGLO...
Les immunoglobulines sont des glycoprotéines présentes dans le sérum, les liquides extra-vasculaires, ... Les dosages d'immunoglobulines (Ig) sont des examens fréquents, utilisés dans l'exploration de l'immunité humorale. ... VARIATIONS PHYSIOLOGIQUES. ▫ Age : IgG : le nouveau-né ne synthétise qu'une faible ...
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9 hrs

natural immunoglobulins

,,
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