Glossary entry

Spanish term or phrase:

Infiltrado inflamatorio moderado peri e intratumoral por linfocitos

English translation:

moderate peri-and intratumoral inflammatory lymphocytic (and plasma cell) infiltrate

Added to glossary by Charles Davis
May 30, 2019 14:31
4 yrs ago
16 viewers *
Spanish term

Infiltrado inflamatorio moderado peri e intratumoral por linfocitos

Spanish to English Medical Medical (general)
Hola, estoy traduciendo un informe anatomopatológico sobre cáncer de mama. En la descripción microscópica dice:

"En el estroma se observa desmoplasia moderada y degeneración mixoide e infiltrado inflamatorio moderado peri e intratumoral por linforcitos y células plasmáticas"

¿Alguna sugerencia?

Gracias de antemano!!
Change log

Jun 4, 2019 13:05: Charles Davis Created KOG entry

Proposed translations

+4
31 mins
Selected

moderate peri-and intratumoral lymphocytic (and plasma cell) infiltrate

"A moderate amount of peri- and intratumoral lymphocytic infiltrate was seen on hematoxylin-eosin (H&E) stain and CD8 immunostain."
"Moderate peri-and intratumoral lymphocytic infiltrate is highlighted by CD8 immunostain."
From an article by a group at Yale University School of Medicine. Clin Cancer Res
. 2016 December 1; 22(23): 5682–5687
https://www.researchgate.net/publication/305803426_Regressio...

"The large majority (94%) of ductal tumours had evidence of inflammatory cell infiltrate. [...] On univariate analysis, stratified for ER status, tumour size (P<0.01), lymph node involvement (P<0.001), tumour plasma cell infiltrate (P<0.001), other inflammatory cell infiltrate (P<0.05) and treatment (P<0.05) were associated with poorer cancer-specific survival"
Mohammed ZM, Going JJ, Edwards J, Elsberger B, Doughty JC, McMillan DC. The relationship between components of tumour inflammatory cell infiltrate and clinicopathological factors and survival in patients with primary operable invasive ductal breast cancer. Br J Cancer. 2012 Aug 21;107(5):864-73
https://www.ncbi.nlm.nih.gov/pubmed/22878371


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Note added at 35 mins (2019-05-30 15:07:21 GMT)
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Sorry, I missed out "inflamatorio". It should be:

moderate inflammatory peri-and intratumoral lymphocytic infiltrate


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Note added at 40 mins (2019-05-30 15:11:49 GMT)
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Or moderate peri- and intratumoral inflammatory lymphocytic infiltrate if you prefer.

"at dermo-hypodermal level we can observe moderate inflammatory lymphocytic infiltrate"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876001/
Peer comment(s):

agree raptisi
23 mins
Many thanks, raptisi :-)
agree Chema Nieto Castañón
27 mins
Many thanks, Chema ;-)
agree María Patricia Arce : also lymphoplasmacytic infiltrate
1 hr
You're right! Thanks very much, María Patricia :-)
agree JohnMcDove
2 hrs
Muchas gracias, John ;-) ¡Menudo trabalenguas!
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4 KudoZ points awarded for this answer.
33 mins

moderate peritumoral and intratumoral inflammatory infiltrate consisting of lymphocytes


The stroma showed moderate inflammatory infiltrate consisting of lymphocytes and plasma cells
https://www.omicsonline.org/open-access/oral-inflammatory-my...

In order to quantify the peritumoral inflammatory infiltrate,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556313/

Tumor-infiltrating lymphocytes (TILs) have prognostic significance in breast cancer. ... the presence of peritumoral lymphocytic infiltration, moderate to .... and score 3, florid cup-like inflammatory infiltrate
https://academic.oup.com/ajcp/article/144/2/278/1766794

There were no such associations of lymphocyte infiltration in the tumor. A high density of CD20+ peritumoral lymphocytes is an independent ..
https://bmcclinpathol.biomedcentral.com/articles/10.1186/147...

Histologic evaluation of control and treatment samples also supported a stronger peritumoral and intratumoral inflammatory infiltrate in treated samples (Fig. 5).
https://www.researchgate.net/figure/Representative-example-o...
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